Endoxifen (Z-isomer)
Endoxifen Z-isomer is the most important Tamoxifen metabolite, inducing an anti-estrogenic effect in breast cancer cells expressing ERα. Endoxifen Z-isomer inhibits hERG. This effect is concentration-dependent, with an IC50 value of 1.6 μM.
Catalog Number | E7063 |
Molecular Formula | C10H13NO4 |
CAS# | 112093-28-4 |
Inchi | InChI=1S/C10H13NO4/c1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6/h2-4,12-13H,5,11H2,1H3,(H,14,15)/t10-/m0/s1 |
Inchi Key | CJCSPKMFHVPWAR-JTQLQIEISA-N |
SMILES | CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)N |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/endoxifen-z-isomer.html |
Additional Information | https://file.selleck.cn/downloads/struct/e7063-endoxifen-z-isomer-chemical-structure-tube.png |