GSK1838705A
GSK1838705A is a potent IGF-1R inhibitor with IC50 of 2.0 nM, modestly potent to IR and ALK with IC50 of 1.6 nM and 0.5 nM, respectively, and little activity to other protein kinases.
| Trivial name | N/A |
| Catalog Number | S2703 |
| Molecular Formula | C27H29FN8O3 |
| CAS# | 1116235-97-2 |
| Inchi | InChI=1S/C27H29FN8O3/c1-29-26(38)23-17(28)6-5-7-18(23)31-25-16-8-10-30-24(16)33-27(34-25)32-19-13-20-15(12-21(19)39-4)9-11-36(20)22(37)14-35(2)3/h5-8,10,12-13H,9,11,14H2,1-4H3,(H,29,38)(H3,30,31,32,33 ,34) |
| Inchi Key | HZTYDQRUAWIZRE-UHFFFAOYSA-N |
| SMILES | CNC(=O)C1=C(C=CC=C1F)NC2=NC(=NC3=C2C=CN3)NC4=C(C=C5CCN(C5=C4)C(=O)CN(C)C)OC |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/gsk1838705a.html |
| Additional Information | https://file.selleck.cn/downloads/struct/GSK1838705A-chemical-structure-s2703.gif |