Metformin HCl
Metformin HCl (1,1-Dimethylbiguanide HCl) decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). Metformin promotes mitophagy in mononuclear cells. Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153.
| Trivial name | 1,1-Dimethylbiguanide HCl |
| Catalog Number | S1950 |
| Molecular Formula | C4H11N5.HCl |
| CAS# | 1115-70-4 |
| Inchi | InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H |
| Inchi Key | OETHQSJEHLVLGH-UHFFFAOYSA-N |
| SMILES | CN(C)C(=N)N=C(N)N.Cl |
| Size | 500mg |
| Supplier Page | http://www.selleckchem.com/products/Metformin-hydrochloride(Glucophage).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Metformin-hydrochloride-Glucophage-chemical-structure-S1950.gif |