Ponatinib hydrochloride

Ponatinib hydrochloride is a potent, orally available multi-targeted inhibitor of Pan BCR-ABL kinase. It potently inhibits ABL with an IC50 of 0.37 nM, also inhibits SRC , VEGFR2, FGFR1, PDGFRα, LYN with an IC50s of 5.4 nM, 1.5 nM, 2.2 nM, 1.1 nM, 0.24 nM respectively and exhibits significant potential in cancer reserach.

Price Not Available 5mg Ponatinib hydrochloride Supplier Page

Trivial name	AP24534 hydrochloride
Catalog Number	E7000
Molecular Formula	C22H25N5O2
CAS#	1114544-31-8
Inchi	InChI=1S/C15H19N5.C7H6O2/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20;8-7(9)6-4-2-1-3-5-6/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3;1-5H,(H,8,9)
Inchi Key	JPRXYLQNJJVCMZ-UHFFFAOYSA-N
SMILES	CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3.C1=CC=C(C=C1)C(=O)O
Size	5mg
Supplier Page	http://www.selleckchem.com/products/ponatinib-hydrochloride.html
Additional Information	https://file.selleck.cn/downloads/struct/E7000-Ponatinib-hydrochloride-chemical-structure.png