Ponatinib (hydrochloride)
An inhibitor of native and mutant Bcr-Abl
| Catalog Number | 35778 |
| Alternative Name(s) | AP 24534 |
| Research Area | Product Type|Biochemicals|Kinase Inhibitors|Abl Family & Bcr-Abl||Product Type|Biochemicals|Kinase Inhibitors|FGFR Family||Product Type|Biochemicals|Kinase Inhibitors|PDGFR Family||Product Type|Biochemicals|Kinase Inhibitors|VEGFR Family||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Signaling|Abl family & Bcr-Abl Signaling||Research Area|Cancer|Cell Signaling|Growth Factor Receptor Signaling||Research Area|Cancer|Multidrug Resistance |
| Molecular Formula | C29H27F3N6O • HCl |
| CAS# | 1114544-31-8 |
| Purity | ≥98% |
| Inchi | InChI=1S/C29H27F3N6O.ClH/c1-20-5-6-22(16-21(20)8-10-25-18-33-27-4-3-11-34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-36(2)13-15-37;/h3-7,9,11,16-18H,12-15,19H2,1-2H3,(H,35,39);1H |
| Inchi Key | BWTNNZPNKQIADY-UHFFFAOYSA-N |
| SMILES | O=C(C1=CC=C(C)C(C#CC2=CN=C3C=CC=NN23)=C1)N([H])C4=CC=C(CN5CCN(CC5)C)C(C(F)(F)F)=C4.Cl |
| Size | 1 g |
| Supplier Page | https://www.caymanchem.com/product/35778 |