Takinib
Takinib is a potent and selective TAK1 inhibitor with an IC50 of 9.5 nM, more than 1.5 log more potent than the second and third ranked targets, IRAK4 (120 nM) and IRAK1 (390 nM), respectively. Takinib induces apoptosis.
| Trivial name | EDHS-206 |
| Catalog Number | S8663 |
| Molecular Formula | C18H18N4O2 |
| CAS# | 1111556-37-6 |
| Inchi | InChI=1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24) |
| Inchi Key | UOZVVPXKJGOFIG-UHFFFAOYSA-N |
| SMILES | CCCN1C2=CC=CC=C2N=C1NC(=O)C3=CC=CC(=C3)C(=O)N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/takinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/takinib-chemical-structure-s8663.jpg |