Dacomitinib

Dacomitinib is an anticancer drug (EGFR inhibitor).

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Catalog Number	API0232656
Alternative Name(s)	(E)-N-(4-((3-chloro-4-fluorophenyl)aMino)-7-Methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enaMide; 829-313-8
Research Area	API
Molecular Formula	C24H25ClFN5O2
CAS#	1110813-31-4
Inchi	InChI=1S/C24H25ClFN5O2/c1-33-22-14-20-17(24(28-15-27-20)29-16-7-8-19(26)18(25)12-16)13-21(22)30-23(32)6-5-11-31-9-3-2-4-10-31/h5-8,12-15H,2-4,9-11H2,1H3,(H,30,32)(H,27,28,29)/b6-5+
Inchi Key	LVXJQMNHJWSHET-AATRIKPKSA-N
SMILES	COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)NC(=O)/C=C/CN4CCCCC4
Size	inquiry
Supplier Page	https://apihub.protheragen.ai/dacomitinib-item-1156.html

Dacomitinib

Dacomitinib is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively.

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Catalog Number	API1110813314
Research Area	Active Pharmaceutical Ingredients
Molecular Formula	C24H25ClFN5O2
CAS#	1110813-31-4
Size	inquiry
Supplier Page	https://www.protheragen.ai/dacomitinib-item-6081.html