Glasdegib
Glasdegib is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2.
| Trivial name | PF-04449913 |
| Catalog Number | S7160 |
| Molecular Formula | C21H22N6O |
| CAS# | 1095173-27-5 |
| Inchi | InChI=1S/C21H22N6O/c1-27-11-10-16(24-21(28)23-15-8-6-14(13-22)7-9-15)12-19(27)20-25-17-4-2-3-5-18(17)26-20/h2-9,16,19H,10-12H2,1H3,(H,25,26)(H2,23,24,28)/t16-,19-/m1/s1 |
| Inchi Key | SFNSLLSYNZWZQG-VQIMIIECSA-N |
| SMILES | CN1CCC(CC1C2=NC3=CC=CC=C3N2)NC(=O)NC4=CC=C(C=C4)C#N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/glasdegib-pf-04449913.html |
| Additional Information | https://file.selleck.cn/downloads/struct/pf-04449913-chemical-structure-s7160.gif |