U0126

Potent and selective non-competitive inhibitor of MAP kinase kinase(MEK). Inhibits MEK-1 and MEK-2 (IC50 values of 0.07 and 0.06 µM respectively) with little or no effect on the activities of PKC, Abl, Raf, MEKK, ERK, JNK, MKK-3, MKK-4/SEK, MKK-6, Cdk2 or Cdk4.

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Catalog Number	ABS-071
Alternative Name(s)	1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene
CAS#	109511-58-2
Inchi	InChI=1S/C18H16N6S2/c19-9-11(17(23)25-15-7-3-1-5-13(15)21)12(10-20)18(24)26-16-8-4-2-6-14(16)22/h1-8H,21-24H2/b17-11+,18-12+
Inchi Key	DVEXZJFMOKTQEZ-JYFOCSDGSA-N
SMILES	C1=CC=C(C(=C1)N)SC(=C(C#N)C(=C(N)SC2=CC=CC=C2N)C#N)N
Size	Inquiry
Supplier Page	https://www.agingclocks.com/u0126-item-1535.html