BIX 02189
BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM, also inhibits ERK5 catalytic activity with IC50 of 59 nM in cell-free assays, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
| Trivial name | N/A |
| Catalog Number | S1531 |
| Molecular Formula | C26H39N7O3 |
| CAS# | 1094614-85-3 |
| SMILES | CC(C)C1=C2N=C(C)C=C(NC3CCN(CC3)C(=O)OC4CCN(C4)C(=O)\C=C\CN(C)C)[N]2N=C1 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/BIX-02189.html |
| Additional Information | https://file.selleck.cn/downloads/struct/BIX02189-chemical-structure-S1531.gif |
