BIX 02188
BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
| Trivial name | N/A |
| Catalog Number | S1530 |
| Molecular Formula | C25H24N4O2 |
| CAS# | 1094614-84-2 |
| Inchi | InChI=1S/C26H26N4O2/c1-27-25(31)19-12-13-21-22(15-19)29-26(32)23(21)24(18-9-5-4-6-10-18)28-20-11-7-8-17(14-20)16-30(2)3/h4-15,28H,16H2,1-3H3,(H,27,31)(H,29,32)/b24-23- |
| Inchi Key | BQNHHYZMVCQLJG-VHXPQNKSSA-N |
| SMILES | CN(C)CC1=CC(=CC=C1)N=C(C2=CC=CC=C2)C3=C(NC4=C3C=CC(=C4)C(=O)N)O |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/BIX-02188.html |
| Additional Information | https://file.selleck.cn/downloads/struct/BIX02188-chemical-structure-S1530.gif |