BI-671800

BI-671800 (AP-761, Cmpd A) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2) with IC50 of 4.5 nM and 3.7 nM for PGD2 binding to human CRTH2 and murine CRTH2, respectively. BI-671800 is associated with a small improvement in FEV1 in symptomatic controller-naïve asthma patients, and in patients on ICS.

Price Not Available 5mg BI-671800 Supplier Page

Trivial name	AP-761, Cmpd A
Catalog Number	S0495
Molecular Formula	C25H26F3N5O3
CAS#	1093108-50-9
SMILES	CN(C)C1=C(C(=NC(=N1)CC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)C(F)(F)F)N(C)C)CC(=O)O
Size	5mg
Supplier Page	http://www.selleckchem.com/products/ap-761-bi671800.html
Additional Information	https://file.selleck.cn/downloads/struct/s0495-bi671800-chemical-structure.gif