PP121
PP-121 is a multi-targeted inhibitor of PDGFR, Hck, mTOR, VEGFR2, Src and Abl with IC50 of 2 nM, 8 nM, 10 nM, 12 nM, 14 nM and 18 nM, also inhibits DNA-PK with IC50 of 60 nM.
Trivial name | N/A |
Catalog Number | S2622 |
Molecular Formula | C17H17N7 |
CAS# | 1092788-83-4 |
Inchi | InChI=1S/C17H17N7/c18-15-13-14(11-7-10-5-6-19-16(10)20-8-11)23-24(12-3-1-2-4-12)17(13)22-9-21-15/h5-9,12H,1-4H2,(H,19,20)(H2,18,21,22) |
Inchi Key | NVRXTLZYXZNATH-UHFFFAOYSA-N |
SMILES | C1CCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CN=C5C(=C4)C=CN5)N |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/PP121.html |
Additional Information | https://file.selleck.cn/downloads/struct/PP-121-chemical-structure-S2622.gif |