(3R,4S)-Tofacitinib

(3R,4S)-Tofacitinib is a less active enantiomer of Tofacitinib and a first-in-class inhibitor of JAK3 with an IC50 of 1 nM. It is highly efficacious in treating rheumatoid arthritis (RA).

Price Not Available 1g (3R,4S)-Tofacitinib Supplier Page

Catalog Number	E6023
Molecular Formula	C21H23Cl2N5O2S
CAS#	1092578-46-5
Inchi	InChI=1S/C21H23Cl2N5O2S/c1-2-25-19(29)17-10-13-18(26-21(24)27-20(13)31-17)12-9-16(15(23)11-14(12)22)30-8-7-28-5-3-4-6-28/h9-11H,2-8H2,1H3,(H,25,29)(H2,24,26,27)
Inchi Key	WJUNQSYQHHIVFX-UHFFFAOYSA-N
SMILES	CCNC(=O)C1=CC2=C(N=C(N=C2S1)N)C3=CC(=C(C=C3Cl)Cl)OCCN4CCCC4
Size	1g
Supplier Page	http://www.selleckchem.com/products/3r,4s-tofacitinib.html
Additional Information	https://file.selleck.cn/downloads/struct/E6023-3R-4S-Tofacitinib-chemical-structure.png