(3R,4S)-Tofacitinib

(3R,4S)-Tofacitinib is a less active enantiomer of Tofacitinib and a first-in-class inhibitor of JAK3 with an IC50 of 1 nM. It is highly efficacious in treating rheumatoid arthritis (RA).

Price Not Available 100mg (3R,4S)-Tofacitinib Supplier Page

Catalog Number	E6023
Molecular Formula	C23H23N7O5
CAS#	1092578-46-5
Inchi	InChI=1S/C23H23N7O5/c1-2-3-14(10-15-11-26-20-18(27-15)19(24)29-23(25)30-20)12-4-6-13(7-5-12)21(33)28-16(22(34)35)8-9-17(31)32/h1,4-7,11,14,16H,3,8-10H2,(H,28,33)(H,31,32)(H,34,35)(H4,24,25,26,29,30)/t 14?,16-/m0/s1
Inchi Key	OGSBUKJUDHAQEA-WMCAAGNKSA-N
SMILES	C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Size	100mg
Supplier Page	http://www.selleckchem.com/products/3r,4s-tofacitinib.html
Additional Information	https://file.selleck.cn/downloads/struct/E6023-3R-4S-Tofacitinib-chemical-structure.png