Torkinib (PP242)
Torkinib (PP242) is a selective mTOR inhibitor with IC50 of 8 nM in cell-free assays; targets both mTOR complexes with >10- and 100-fold selectivity for mTOR than PI3Kδ or PI3Kα/β/γ, respectively. Torkinib (PP242) induces mitophagy and apoptosis.
| Trivial name | N/A |
| Catalog Number | S2218 |
| Molecular Formula | C16H16N6O |
| CAS# | 1092351-67-1 |
| Inchi | InChI=1S/C16H16N6O/c1-8(2)22-16-13(15(17)18-7-19-16)14(21-22)12-6-9-5-10(23)3-4-11(9)20-12/h3-8,20,23H,1-2H3,(H2,17,18,19) |
| Inchi Key | MFAQYJIYDMLAIM-UHFFFAOYSA-N |
| SMILES | CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=C(N3)C=CC(=C4)O)N |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/PP242.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PP242-chemical-structure-S2218.gif |