β-Amyloid (1-42), human

β-Amyloid (1-42), human is a peptide fragment composed of 42 amino acids, derived from amyloid precursor protein (APP), and plays a crucial role in Alzheimer’s disease (AD). It self-aggregates into oligomers and fibrils, with the oligomeric form being the most neurotoxic. These aggregates form amyloid plaques, a characteristic feature of AD, which interfere with cellular functions, cause mitochondrial dysfunction, and lead to neuronal cell death through oxidative stress, calcium dysregulation, and inflammation.

Price Not Available 5mg β-Amyloid (1-42), human Supplier Page
Trivial name Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
Catalog Number P1003
Molecular Formula C10H12O4
CAS# 107761-42-2
Inchi InChI=1S/C10H12O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2,4,6,11H,3,5H2,1H3,(H,12,13)
Inchi Key BOLQJTPHPSDZHR-UHFFFAOYSA-N
SMILES COC1=C(C=CC(=C1)CCC(=O)O)O
Size 5mg
Supplier Page http://www.selleckchem.com/peptide/beta-amyloid-1-42-human.html
Additional Information https://file.selleck.cn/downloads/struct/Beta-Amyloid-1-42-human-chemical-structure-P1003.gif