CY-09
CY-09 is a specific NLRP3 inflammasome inhibitor that directly targeted NLRP3 itself. It is tested against the five major cytochrome P450 enzymes 1A2, 2C9, 2C19, 2D6, and 3A4 with half maximal inhibitory concentration (IC50) values of 18.9, 8.18, >50, >50, and 26.0 µM, respectively.
| Trivial name | N/A |
| Catalog Number | S5774 |
| Molecular Formula | C19H12F3NO3S2 |
| CAS# | 1073612-91-5 |
| Inchi | InChI=1S/C19H12F3NO3S2/c20-19(21,22)14-3-1-2-12(8-14)10-23-16(24)15(28-18(23)27)9-11-4-6-13(7-5-11)17(25)26/h1-9H,10H2,(H,25,26)/b15-9+ |
| Inchi Key | DJTINRHPPGAPLD-OQLLNIDSSA-N |
| SMILES | C1=CC(=CC(=C1)C(F)(F)F)CN2C(=O)C(=CC3=CC=C(C=C3)C(=O)O)SC2=S |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/cy-09.html |
| Additional Information | https://file.selleck.cn/downloads/struct/cy-09-chemical-structure-s5774.gif |