Defactinib hydrochloride
Defactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.
| Trivial name | VS-6063 hydrochloride, PF 04554878 hydrochloride |
| Catalog Number | E7468 |
| Molecular Formula | C11H11F3N2O3 |
| CAS# | 1073160-26-5 |
| Inchi | InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17) |
| Inchi Key | MKXKFYHWDHIYRV-UHFFFAOYSA-N |
| SMILES | CC(C)C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/defactinib-hydrochloride.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7468-defactinib-hydrochloride-chemical-structure-tube.png |
