SN 52
SN52, a cell-permeable peptide containing the p50 NLS, is a selective inhibitor of NF-κB pathway. It selectively and completely blocks the ionizing radiation (IR)-induced nuclear import of p52 and RelB. It also enhances the radiosensitivity of prostate cancer cells.
| Catalog Number | P1238 |
| Molecular Formula | C43H65FN6O10 |
| CAS# | 1071173-56-2 |
| Inchi | InChI=1S/C43H65FN6O10/c1-12-32-43(8)35(50(40(55)60-43)19-14-13-18-49-23-30(46-47-49)28-16-15-17-29(45)21-28)26(4)33(51)24(2)22-41(6,56-11)37(27(5)36(53)42(7,44)39(54)58-32)59-38-34(52)31(48(9)10)20-25 (3)57-38/h15-17,21,23-27,31-32,34-35,37-38,52H,12-14,18-20,22,45H2,1-11H3/t24-,25-,26-,27+,31+,32+,34-,35-,37-,38+,41-,42-,43-/m1/s1 |
| Inchi Key | IXXFZUPTQVDPPK-RTMQOTFBSA-N |
| SMILES | CCC1C2(C(C(C(=O)C(CC(C(C(C(=O)C(C(=O)O1)(C)F)C)OC3C(C(CC(O3)C)N(C)C)O)(C)OC)C)C)N(C(=O)O2)CCCCN4C=C(N=N4)C5=CC(=CC=C5)N)C |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/sn-52.html |
| Additional Information | https://file.selleck.cn/downloads/struct/P1238-SN-52-chemical-structure.png |