RK-33
RK-33 is a first-in-class small molecule inhibitor of DDX3 (a RNA helicase) and causes G1 cell cycle arrest, induces apoptosis, and promotes radiation sensitization in DDX3-overexpressing cells.
| Trivial name | N/A |
| Catalog Number | S8246 |
| Molecular Formula | C23H20N6O3 |
| CAS# | 1070773-09-9 |
| Inchi | InChI=1S/C23H20N6O3/c1-31-17-7-3-15(4-8-17)11-28-14-26-19-20-22(25-13-24-21(19)28)29(23(30)27-20)12-16-5-9-18(32-2)10-6-16/h3-10,13-14H,11-12H2,1-2H3 |
| Inchi Key | COUMZXFUZDBRCZ-UHFFFAOYSA-N |
| SMILES | COC1=CC=C(C=C1)CN2C=NC3=C2N=CN=C4C3=NC(=O)N4CC5=CC=C(C=C5)OC |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/rk-33.html |
| Additional Information | https://file.selleck.cn/downloads/struct/rk-33-chemical-structure-s8246.gif |