Valproic Acid sodium

Valproic Acid sodium is a HDAC inhibitor by selectively inducing proteasomal degradation of HDAC2, used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Valproic acid induces Notch1 signaling in small cell lung cancer (SCLC) cells. Valproic acid is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α.

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Trivial name Sodium valproate,NSC 93819,2-Propylpentanoic Acid
Catalog Number S1168
Molecular Formula C8H15NaO2
CAS# 1069-66-5
Inchi InChI=1S/C8H16O2.Na/c1-3-5-7(6-4-2)8(9)10;/h7H,3-6H2,1-2H3,(H,9,10);/q;+1/p-1
Inchi Key AEQFSUDEHCCHBT-UHFFFAOYSA-M
SMILES CCCC(CCC)C(=O)[O-].[Na+]
Size 10mM/1mL
Supplier Page http://www.selleckchem.com/products/Sodium-valproate.html
Additional Information https://file.selleck.cn/downloads/struct/Valproate-chemical-structure-S1168.gif