Valproic Acid sodium

Valproic Acid sodium is a HDAC inhibitor by selectively inducing proteasomal degradation of HDAC2, used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Valproic acid induces Notch1 signaling in small cell lung cancer (SCLC) cells. Valproic acid is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α.

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Trivial name	Sodium valproate,NSC 93819,2-Propylpentanoic Acid
Catalog Number	S1168
Molecular Formula	C8H15NaO2
CAS#	1069-66-5
Inchi	InChI=1S/C8H16O2.Na/c1-3-5-7(6-4-2)8(9)10;/h7H,3-6H2,1-2H3,(H,9,10);/q;+1/p-1
Inchi Key	AEQFSUDEHCCHBT-UHFFFAOYSA-M
SMILES	CCCC(CCC)C(=O)[O-].[Na+]
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/Sodium-valproate.html
Additional Information	https://file.selleck.cn/downloads/struct/Valproate-chemical-structure-S1168.gif