Wortmannin-Rapamycin Conjugate

Separate PI3K and mTORC1 inhibitors joined by prodrug linker

Catalog Number 13671
Research Area Adaptive Immunity|Apoptosis|Autophagy|Cancer|Cell Biology|Cell Death|Cell Signaling|Diabetes|Endocrinology & Metabolism|Endomembrane System & Vesicular Trafficking|Immunology & Inflammation|Immunosuppressants|Metabolic Diseases|Obesity|PI3K/Akt/mTOR Signaling
Molecular Formula C88H131N3O23
CAS# 1067892-47-0
Purity ≥98%
Inchi InChI=1S/C88H131N3O23/c1-51-28-21-20-22-29-52(2)66(106-15)46-60-35-33-57(7)88(104,114-60)82(100)83(101)91-41-26-25-30-63(91)85(103)111-67(47-64(93)53(3)43-56(6)78(97)81(108-17)77(96)55(5)42-51)54(4)44-59-34-37-65(68(45-59)107-16)110-72(94)31-23-18-19-24-32-73(95)112-70-38-36-62-74-76(69(109-58(8)92)48-86(62,70)9)87(10)71(50-105-14)113-84(102)61(75(87)80(99)79(74)98)49-90(13)40-27-39-89(11)12/h20-22,28-29,43,49,51,53-55,57,59-60,62-63,65-71,78,81,97,99,104H,18-19,23-27,30-42,44-48,50H2,1-17H3/b22-20+,28-21+,52-29+,56-43+,61-49+/t51-,53-,54-,55-,57-,59+,60+,62+,63+,65-,66+,67+,68-,69-,70+,71-,78-,81+,86+,87+,88-/m1/s1
Inchi Key GVMCLKAVNVFURS-UXLLMVCWSA-N
SMILES O=C(O[C@H]1[C@H](OC)C[C@H](C[C@@H](C)[C@@](CC([C@H](C)/C=C(C)/[C@@H](O)[C@@H](OC)C([C@H](C)C[C@H](C)/C=C/C=C/C=C(C)/[C@@H](OC)C[C@](O2)([H])CC[C@@H](C)[C@]2(O)C3=O)=O)=O)([H])OC([C@]4([H])CCCCN4C3=O)=O)CC1)CCCCCCC(O[C@H]5CC[C@]6([H])[C@]5(C)C[C@@H](OC(C)=O)C([C@]([C@@H](COC)OC(/C7=C/N(C)CCCN(C)C)=O)(C)C7=C8O)=C6C8=O)=O
Size 5 mg
Supplier Page https://www.caymanchem.com/product/13671