ML347
ML347 (LDN-193719) is a selective BMP receptor inhibitor with IC50 of 32 nM for ALK2, >300-fold selectivity over ALK3. Also inhibits ALK1 activity with IC50 of 46 nM.
| Trivial name | LDN-193719 |
| Catalog Number | S7148 |
| Molecular Formula | C22 H16 N4 O |
| CAS# | 1062368-49-3 |
| Inchi | InChI=1S/C22H16N4O/c1-27-17-9-7-15(8-10-17)16-12-24-22-20(13-25-26(22)14-16)18-4-2-6-21-19(18)5-3-11-23-21/h2-14H,1H3 |
| Inchi Key | FVRYPYDPKSZGNS-UHFFFAOYSA-N |
| SMILES | COC1=CC=C(C=C1)C2=CN3C(=C(C=N3)C4=C5C=CC=NC5=CC=C4)N=C2 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ml347.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ML347-chemical-structure-s7148.gif |