Ro3280
RO3280 (Ro5203280) is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM.
| Trivial name | Ro5203280 |
| Catalog Number | S7248 |
| Molecular Formula | C27H35F2N7O3 |
| CAS# | 1062243-51-9 |
| Inchi | InChI=1S/C27H35F2N7O3/c1-34-12-10-18(11-13-34)31-24(37)17-8-9-20(22(14-17)39-3)32-26-30-15-21-23(33-26)36(19-6-4-5-7-19)16-27(28,29)25(38)35(21)2/h8-9,14-15,18-19H,4-7,10-13,16H2,1-3H3,(H,31,37)(H,30, 32,33) |
| Inchi Key | DJNZZLZKAXGMMC-UHFFFAOYSA-N |
| SMILES | CN1CCC(CC1)NC(=O)C2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(CC(C(=O)N4C)(F)F)C5CCCC5)OC |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/ro3280.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Ro5203280-chemical-structure-s7248.gif |