mTOR Inhibitor, WYE-28
Cell-permeable. A potent, selective, and ATP-competitive mTOR (mammalian Target Of Rapamycin) inhibitor (IC50 = 0.08 nM). Displays 75-fold selectivity over PI3Kα (IC50 = 6 nM).
| Catalog Number | ABM-011 |
| Alternative Name(s) | 4-(6-{4-[3-(4-Hydroxymethyl-phenyl)-ureido]-phenyl}-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidine-1-carboxylic acid methyl ester |
| CAS# | 1062172-60-4 |
| Inchi | InChI=1S/C30H34N8O5/c1-42-30(41)37-12-10-24(11-13-37)38-28-25(18-31-38)27(36-14-16-43-17-15-36)34-26(35-28)21-4-8-23(9-5-21)33-29(40)32-22-6-2-20(19-39)3-7-22/h2-9,18,24,39H,10-17,19H2,1H3,(H2,32,33,40) |
| Inchi Key | DLIGFKRUAOAIBA-UHFFFAOYSA-N |
| SMILES | COC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)NC(=O)NC5=CC=C(C=C5)CO)N6CCOCC6 |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/mtor-inhibitor-wye-28-item-1456.html |