WYE-354

WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kα (>100-fold) and PI3Kγ (>500-fold).

Price Not Available 5 mg WYE-354 Supplier Page

Catalog Number	T6731
Research Area	Apoptosis\|\|\|PI3K/Akt/mTOR signaling\|\|\|Autophagy
Molecular Formula	C24H29N7O5
CAS#	1062169-56-5
Purity	98.31%
SMILES	COC(=O)Nc1ccc(cc1)c1nc2c(cnn2C2CCN(CC2)C(=O)OC)c(n1)N1CCOCC1
Size	5 mg
Supplier Page	https://www.targetmol.com/compound/WYE-354
Additional Information	https://www.targetmol.com/datasheet/T6731