mTOR Inhibitor, WYE-23
Cell-permeable. A potent, selective, and ATP-competitive mTOR (mammalian Target Of Rapamycin) inhibitor (IC50 = 0.45 nM nM). Displays 1469-fold selectivity over PI3Kα (IC50 = 661 nM).
| Catalog Number | ABM-010 |
| Alternative Name(s) | 4-{6-[4-(3-Cyclopropyl-ureido)-phenyl]-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl}-piperidine-1-carboxylic acid methyl ester |
| CAS# | 1062169-46-3 |
| Inchi | InChI=1S/C26H32N8O4/c1-37-26(36)33-10-8-20(9-11-33)34-24-21(16-27-34)23(32-12-14-38-15-13-32)30-22(31-24)17-2-4-18(5-3-17)28-25(35)29-19-6-7-19/h2-5,16,19-20H,6-15H2,1H3,(H2,28,29,35) |
| Inchi Key | NQNFBVOZVJAWSQ-UHFFFAOYSA-N |
| SMILES | COC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)NC(=O)NC5CC5)N6CCOCC6 |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/mtor-inhibitor-wye-23-item-1455.html |