WYE-687
WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(T308). Selectivity for mTOR is greater than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
Trivial name | N/A |
Catalog Number | S2668 |
Molecular Formula | C24H24N4O5S |
CAS# | 1062161-90-3 |
SMILES | CC(C1=NC=CS1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)OC |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/wye-687.html |
Additional Information | https://file.selleck.cn/downloads/struct/WYE-687-chemical-structure-s2668.gif |