WAY-600
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
| Trivial name | N/A |
| Catalog Number | S2689 |
| Molecular Formula | C28H30N8O |
| CAS# | 1062159-35-6 |
| Inchi | InChI=1S/C28H30N8O/c1-2-20(17-29-8-1)19-34-10-6-23(7-11-34)36-28-24(18-31-36)27(35-12-14-37-15-13-35)32-26(33-28)22-3-4-25-21(16-22)5-9-30-25/h1-5,8-9,16-18,23,30H,6-7,10-15,19H2 |
| Inchi Key | FPEIJQLXFHKLJV-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1N2C3=C(C=N2)C(=NC(=N3)C4=CC5=C(C=C4)NC=C5)N6CCOCC6)CC7=CN=CC=C7 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/way-600.html |
| Additional Information | https://file.selleck.cn/downloads/struct/WAY-600-chemical-structure-s2689.gif |