VS-4718 (PND-1186)
VS-4718 (PND-1186) is a reversible and selective FAK inhibitor with IC50 of 1.5 nM. PND-1186 selectively promotes tumor cell apoptosis. Phase 1.
| Trivial name | SR-2156 |
| Catalog Number | S7653 |
| Molecular Formula | C25H26F3N5O3 |
| CAS# | 1061353-68-1 |
| Inchi | InChI=1S/C25H26F3N5O3/c1-29-24(34)17-5-3-4-6-19(17)31-21-14-23(30-15-18(21)25(26,27)28)32-20-8-7-16(13-22(20)35-2)33-9-11-36-12-10-33/h3-8,13-15H,9-12H2,1-2H3,(H,29,34)(H2,30,31,32) |
| Inchi Key | IGUBBWJDMLCRIK-UHFFFAOYSA-N |
| SMILES | CNC(=O)C1=CC=CC=C1NC2=CC(=NC=C2C(F)(F)F)NC3=C(C=C(C=C3)N4CCOCC4)OC |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/pnd-1186-vs-4718.html |
| Additional Information | https://file.selleck.cn/downloads/struct/pnd-1186-vs-471-chemical-structure-s7653.gif |