Dehydrocorydaline chloride
Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid that regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline chloride elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities. Dehydrocorydaline chloride shows strong anti-malarial effects (IC50 =38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain.
| Trivial name | 13-Methylpalmatine chloride |
| Catalog Number | E7458 |
| Molecular Formula | C14H10Cl2NNaO2 |
| CAS# | 10605-03-5 |
| Inchi | InChI=1S/C14H11Cl2NO2.Na/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;/h1-7,17H,8H2,(H,18,19);/q;+1/p-1 |
| Inchi Key | KPHWPUGNDIVLNH-UHFFFAOYSA-M |
| SMILES | C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2Cl)Cl.[Na+] |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/dehydrocorydaline-chloride.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7458-dehydrocorydaline-chloride-chemical-structure-tube.png |