Momelotinib (CYT387)

Momelotinib (CYT387, LM-1149 , CYT11387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3. Momelotinib (CYT387) induces apoptosis and autophagy. Phase 3.

Price Not Available 50mg Momelotinib (CYT387) Supplier Page
Trivial name LM-1149 , CYT11387
Catalog Number S2219
Molecular Formula C23H22N6O2
CAS# 1056634-68-4
Inchi InChI=1S/C23H22N6O2/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)27-19-5-7-20(8-6-19)29-13-15-31-16-14-29/h1-9,11H,12-16H2,(H,25,30)(H,26,27,28)
Inchi Key ZVHNDZWQTBEVRY-UHFFFAOYSA-N
SMILES C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N
Size 50mg
Supplier Page http://www.selleckchem.com/products/Cyt387.html
Additional Information https://file.selleck.cn/downloads/struct/CYT-387-chemical-structure-S2219.gif