Tamoxifen
API Standard
| Catalog Number | CS-T-43118 |
| Alternative Name(s) | (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine |
| Research Area | Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells. |
| Molecular Formula | C26H29NO |
| CAS# | 10540-29-1 |
| Purity | >98% |
| SMILES | CC/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(C)C)C=C3 |
| Size | 500 g |
| Supplier Page | https://www.clearsynth.com/en/CST43118.html |