Cabotegravir (GSK1265744)
Cabotegravir (GSK744, GSK1265744, S/GSK1265744) is a long-acting HIV integrase inhibitor against a broad range of HIV subtypes, and inhibits the HIV-1 integrase catalyzed strand transfer reaction with IC50 of 3.0 nM. Phase 2.
Trivial name | GSK744, S/GSK1265744 |
Catalog Number | S7766 |
Molecular Formula | C19H17F2N3O5 |
CAS# | 1051375-10-0 |
Inchi | InChI=1S/C19H17F2N3O5/c1-9-8-29-14-7-23-6-12(16(25)17(26)15(23)19(28)24(9)14)18(27)22-5-10-2-3-11(20)4-13(10)21/h2-4,6,9,14,26H,5,7-8H2,1H3,(H,22,27)/t9-,14+/m0/s1 |
Inchi Key | WCWSTNLSLKSJPK-LKFCYVNXSA-N |
SMILES | CC1COC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/cabotegravir-gsk744-gsk1265744.html |
Additional Information | https://file.selleck.cn/downloads/struct/gsk1265744-chemical-structure-s7766.gif |