Allitinib tosylate

Allitinib tosylate (AST-1306 TsOH, AST-6) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells, 3000-fold selective for ErbB family than other kinases.

Price Not Available 5mg Allitinib tosylate Supplier Page

Trivial name	AST-1306 TsOH, AST-6
Catalog Number	S2185
Molecular Formula	C24H18ClFN4O2,C7H8O3S
CAS#	1050500-29-2
Inchi	InChI=1S/C24H18ClFN4O2.C7H8O3S/c1-2-23(31)29-17-6-8-21-19(11-17)24(28-14-27-21)30-18-7-9-22(20(25)12-18)32-13-15-4-3-5-16(26)10-15;1-6-2-4-7(5-3-6)11(8,9)10/h2-12,14H,1,13H2,(H,29,31)(H,27,28,30);2-5H ,1H3,(H,8,9,10)
Inchi Key	ZMUKJEHWLJBODV-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)S(=O)(=O)O.C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=C(C=C3)OCC4=CC(=CC=C4)F)Cl
Size	5mg
Supplier Page	http://www.selleckchem.com/products/allitinib-tosylate.html
Additional Information	https://file.selleck.cn/downloads/struct/AST-1306-chemical-structure-s2185.gif