Afuresertib hydrochloride
Afuresertib hydrochloride (GSK 2110183 hydrochloride) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively.
Trivial name | GSK2110183 hydrochloride; LAE002 hydrochloride |
Catalog Number | E4992 |
Molecular Formula | C26H27NO9.HCl |
CAS# | 1047645-82-8 |
Inchi | InChI=1S/C26H27NO9.ClH/c1-10-21(29)15(27)7-17(35-10)36-16-9-26(34,11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31;/h3-6,10,15-17,21,29,32-34H,7-9,27H2,1-2H3;1H/t10-,15-,16-,17- ,21+,26-;/m0./s1 |
Inchi Key | JVHPTYWUBOQMBP-RVFAQHLVSA-N |
SMILES | CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O.Cl |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/afuresertib-hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4992-Afuresertib-hydrochloride-chemical-structure.png |