Uprosertib (GSK2141795)

Uprosertib (GSK2141795, GSK795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2.

Price Not Available 10mM/1mL Uprosertib (GSK2141795) Supplier Page

Trivial name	GSK795
Catalog Number	S7492
Molecular Formula	C18H16Cl2F2N4O2
CAS#	1047634-65-0
Inchi	InChI=1S/C18H16Cl2F2N4O2/c1-26-16(12(19)8-24-26)11-6-15(28-17(11)20)18(27)25-10(7-23)4-9-2-3-13(21)14(22)5-9/h2-3,5-6,8,10H,4,7,23H2,1H3,(H,25,27)/t10-/m0/s1
Inchi Key	AXTAPYRUEKNRBA-JTQLQIEISA-N
SMILES	CN1C(=C(C=N1)Cl)C2=C(OC(=C2)C(=O)NC(CC3=CC(=C(C=C3)F)F)CN)Cl
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/gsk2141795.html
Additional Information	https://file.selleck.cn/downloads/struct/gsk2141795-chemical-structure-s7492.gif