Niraparib
MK-4827(Niraparib) is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.
| Catalog Number | T3231 |
| Alternative Name(s) | MK-4827 |
| Research Area | Others|||DNA Damage/DNA Repair|||Apoptosis|||Chromatin/Epigenetic |
| Molecular Formula | C19H20N4O |
| CAS# | 1038915-60-4 |
| Purity | 99.48% |
| SMILES | c1(cccc2c1nn(c2)c1ccc(cc1)[C@H]1CNCCC1)C(=O)N |
| Size | 25 mg |
| Supplier Page | https://www.targetmol.com/compound/Niraparib |
| Additional Information | https://www.targetmol.com/datasheet/T3231 |
