Fexagratinib (AZD4547)

Fexagratinib (AZD4547,ABSK 091) is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM in cell-free assays, weaker activity against FGFR4, VEGFR2(KDR), and little activity observed against IGFR, CDK2, and p38. Phase 2/3.

Price Not Available 10mM/1mL Fexagratinib (AZD4547) Supplier Page

Trivial name	ABSK 091
Catalog Number	S2801
Molecular Formula	C38H38N6O3S
CAS#	1035270-39-3
Inchi	InChI=1S/C38H38N6O3S/c1-22-29(19-39-44(22)21-38-16-23-13-24(17-38)15-25(14-23)18-38)27-9-10-33(41-34(27)36(46)47)43-12-11-26-5-4-6-28(30(26)20-43)35(45)42-37-40-31-7-2-3-8-32(31)48-37/h2-10,19,23-25H, 11-18,20-21H2,1H3,(H,46,47)(H,40,42,45)
Inchi Key	QCQQONWEDCOTBV-UHFFFAOYSA-N
SMILES	CC1=C(C=NN1CC23CC4CC(C2)CC(C4)C3)C5=C(N=C(C=C5)N6CCC7=C(C6)C(=CC=C7)C(=O)NC8=NC9=CC=CC=C9S8)C(=O)O
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/azd4547.html
Additional Information	https://file.selleck.cn/downloads/struct/AZD4547-chemical-structure-s2801.gif