Onvansertib (NMS-P937)
Onvansertib (NMS-P937, PCM-075, NMS1286937) is an orally available, selective Polo-like Kinase 1 (PLK1) inhibitor with IC50 of 2 nM, 5000-fold selectivity over PLK2/PLK3. Onvansertib (NMS-P937) potently causes a mitotic cell-cycle arrest followed by apoptosis in cancer cell lines and inhibits tumor growth. Phase 1.
| Trivial name | PCM-075, NMS1286937 |
| Catalog Number | S7255 |
| CAS# | 1034616-18-6 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/nms-p937-nms1286937.html |
| Additional Information | https://file.selleck.cn/downloads/struct/nms-p937-chemical-structure-s7255.gif |