GNE-477
GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with an IC50 of 4 nM for PI3Kα and Kiapp of 21 nM for mTOR.
| Trivial name | N/A |
| Catalog Number | S6516 |
| Molecular Formula | C21H28N8O3S2 |
| CAS# | 1032754-81-6 |
| Inchi | InChI=1S/C21H28N8O3S2/c1-14-16(13-27-3-5-29(6-4-27)34(2,30)31)33-18-17(14)25-19(15-11-23-21(22)24-12-15)26-20(18)28-7-9-32-10-8-28/h11-12H,3-10,13H2,1-2H3,(H2,22,23,24) |
| Inchi Key | AKKCGLXULFRAET-UHFFFAOYSA-N |
| SMILES | CC1=C(SC2=C1N=C(N=C2N3CCOCC3)C4=CN=C(N=C4)N)CN5CCN(CC5)S(=O)(=O)C |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/gne-477.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gne-477-chemical-structure-s6516.gif |