MK-8245
MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. Phase 2.
| Trivial name | N/A |
| Catalog Number | S1158 |
| Molecular Formula | C22H32O2 |
| CAS# | 1030612-90-8 |
| Inchi | InChI=1S/C22H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-21H2,1H3,(H,23,24)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18- |
| Inchi Key | MBMBGCFOFBJSGT-KUBAVDMBSA-N |
| SMILES | CCC=CCC=CCC=CCC=CCC=CCC=CCCC(=O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/mk-8245.html |
| Additional Information | https://file.selleck.cn/downloads/struct/MK-8245-chemical-structure-s1158.gif |