MK-8245

MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. Phase 2.

Price Not Available 10mg MK-8245 Supplier Page
Trivial name N/A
Catalog Number S1158
Molecular Formula C17H16BrFN6O4
CAS# 1030612-90-8
Inchi InChI=1S/C17H16BrFN6O4/c18-12-2-1-10(19)7-13(12)28-11-3-5-24(6-4-11)15-8-14(29-22-15)17-20-23-25(21-17)9-16(26)27/h1-2,7-8,11H,3-6,9H2,(H,26,27)
Inchi Key UJEAABFSXKCSGI-UHFFFAOYSA-N
SMILES C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NOC(=C3)C4=NN(N=N4)CC(=O)O
Size 10mg
Supplier Page http://www.selleckchem.com/products/mk-8245.html
Additional Information https://file.selleck.cn/downloads/struct/MK-8245-chemical-structure-s1158.gif