Alisertib (MLN8237)
Alisertib (MLN8237) is a selective Aurora A inhibitor with IC50 of 1.2 nM in a cell-free assay. It has >200-fold higher selectivity for Aurora A than Aurora B. Alisertib induces cell cycle arrest, apoptosis and autophagy. Phase 3.
Trivial name | N/A |
Catalog Number | S1133 |
Molecular Formula | C24H24N4O2 |
CAS# | 1028486-01-2 |
Inchi | #N/A |
Inchi Key | #N/A |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/MLN8237.html |
Additional Information | https://file.selleck.cn/downloads/struct/MLN8237-chemical-structure-S1133.gif |