Dactolisib Tosylate

Dactolisib Tosylate (BEZ235 Tosylate, NVP-BEZ 235 Tosylate) is an imidazo[4,5-c]quinoline derivative and dual inhibitor of PI3K/mTOR with IC50 values of 4, 75, 7, and 5 nM for PI3Kα, β, γ, and δ, respectively. It blocks mTORC1/mTORC2 and demonstrates potent antitumor activity in experimental cancer models.

Price Not Available 5mg Dactolisib Tosylate Supplier Page

Trivial name	BEZ235 Tosylate, NVP-BEZ 235 Tosylate
Catalog Number	E5809
Molecular Formula	C24H28N2O5.HCl
CAS#	1028385-32-1
Inchi	InChI=1S/C24H28N2O5.ClH/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28;/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28);1H/t19-,20-;/m0./s1
Inchi Key	VPSRQEHTHIMDQM-FKLPMGAJSA-N
SMILES	CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=CC=CC=C3N(C2=O)CC(=O)O.Cl
Size	5mg
Supplier Page	http://www.selleckchem.com/products/dactolisib-tosylate.html
Additional Information	https://file.selleck.cn/downloads/struct/E5809-Dactolisib-Tosylate-chemical-structure.png