Lifitegrast
Lifitegrast (SAR1118,SHP-606) is a novel small molecule integrin antagonist that inhibits a specific T cell-mediated inflammatory pathway involved in the pathogenesis of DED.
Trivial name | SAR1118,SHP-606 |
Catalog Number | S3714 |
Molecular Formula | C29H24Cl2N2O7S |
CAS# | 1025967-78-5 |
Inchi | InChI=1S/C29H24Cl2N2O7S/c1-41(38,39)20-4-2-3-16(11-20)12-23(29(36)37)32-27(34)25-22(30)13-19-15-33(9-7-21(19)26(25)31)28(35)18-6-5-17-8-10-40-24(17)14-18/h2-6,8,10-11,13-14,23H,7,9,12,15H2,1H3,(H,32,3 4)(H,36,37)/t23-/m0/s1 |
Inchi Key | JFOZKMSJYSPYLN-QHCPKHFHSA-N |
SMILES | CS(=O)(=O)C1=CC=CC(=C1)CC(C(=O)O)NC(=O)C2=C(C=C3CN(CCC3=C2Cl)C(=O)C4=CC5=C(C=C4)C=CO5)Cl |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/lifitegrast.html |
Additional Information | https://file.selleck.cn/downloads/struct/lifitegrast-chemical-structure-s3714.gif |