Valbenazine
Valbenazine(Ingrezza, Mt-5199, NBI-98854, VBZ) is a potent inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki of 110–190 nM. It is used to treat tardive dyskinesia and chorea associated with Huntington’s disease.
| Trivial name | Ingrezza, Mt-5199, NBI-98854, VBZ |
| Catalog Number | E4844 |
| Molecular Formula | C29H31N5O4 |
| CAS# | 1025504-45-3 |
| Inchi | InChI=1S/C29H31N5O4/c1-36-26-18-24-25(19-27(26)38-15-5-12-34-13-16-37-17-14-34)30-20-31-28(24)32-22-8-10-23(11-9-22)33-29(35)21-6-3-2-4-7-21/h2-4,6-11,18-20H,5,12-17H2,1H3,(H,33,35)(H,30,31,32) |
| Inchi Key | OGNYUTNQZVRGMN-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/valbenazine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4844-Valbenazine-chemical-structure.png |