SGI-1776 free base

SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin. SGI-1776 induces apoptosis and autophagy.

Price Not Available 5mg SGI-1776 free base Supplier Page

Trivial name	N/A
Catalog Number	S2198
Molecular Formula	C20H22F3N5O
CAS#	1025065-69-3
Inchi	InChI=1S/C20H22F3N5O/c1-27-9-7-14(8-10-27)12-24-18-5-6-19-25-13-17(28(19)26-18)15-3-2-4-16(11-15)29-20(21,22)23/h2-6,11,13-14H,7-10,12H2,1H3,(H,24,26)
Inchi Key	MHXGEROHKGDZGO-UHFFFAOYSA-N
SMILES	CN1CCC(CC1)CNC2=NN3C(=NC=C3C4=CC(=CC=C4)OC(F)(F)F)C=C2
Size	5mg
Supplier Page	http://www.selleckchem.com/products/SGI-1776.html
Additional Information	https://file.selleck.cn/downloads/struct/SGI-1776-chemical-structure-S2198.gif