Rebastinib
DCC-2036 (Rebastinib) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC, HCK, FGR, FLT3, KDR, and Tie-2, and low activity to c-Kit. Rebastinib aimed at the Angiopoietin2-Tie2 pathway.

Catalog Number | T2640 |
Alternative Name(s) | DCC2036 , DCC 2036 , DCC-2036 |
Research Area | Apoptosis|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling |
Molecular Formula | C30H28FN7O3 |
CAS# | 1020172-07-9 |
SMILES | CNC(=O)c1nccc(Oc2cc(F)c(NC(=O)Nc3cc(nn3c3cc4c(cc3)nccc4)C(C)(C)C)cc2)c1 |
Size | 2 mg |
Supplier Page | https://www.targetmol.com/compound/Rebastinib |
Additional Information | https://www.targetmol.com/datasheet/T2640 |